BMC | Clinical Proteomics on Feedspot

Proteomics study of primary and recurrent adamantinomatous craniopharyngiomas

BMC | Clinical Proteomics

by Haidong Deng, Ting Lei, Siqi Liu, Wenzhe Hao, Mengqing Hu, Xin Xiang, Ling Ye, Dongting Chen, Yan Li and Fangjun Liu

1w ago

Adamantinomatous craniopharyngiomas (ACPs) are rare benign epithelial tumours with high recurrence and poor prognosis. Biological differences between recurrent and primary ACPs that may be associated with dise ..read more

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Plasma proteomic characterization of colorectal cancer patients with FOLFOX chemotherapy by integrated proteomics technology

BMC | Clinical Proteomics

by Xi Wang, Keren Zhang, Wan He, Luobin Zhang, Biwei Gao, Ruijun Tian and Ruilian Xu

1w ago

Colorectal Cancer (CRC) is a prevalent form of cancer, and the effectiveness of the main postoperative chemotherapy treatment, FOLFOX, varies among patients. In this study, we aimed to identify potential bioma ..read more

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The relationship between serum astroglial and neuronal markers and AQP4 and MOG autoantibodies

BMC | Clinical Proteomics

by Miyo K. Chatanaka, Lisa M. Avery, Maria D. Pasic, Shanthan Sithravadivel, Dalia Rotstein, Catherine Demos, Rachel Cohen, Taron Gorham, Mingyue Wang, Martin Stengelin, Anu Mathew, George Sigal, Jacob Wohlstadter, Ioannis Prassas and Eleftherios P. Diamandis

1w ago

Certain demyelinating disorders, such as neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) exhibit serum autoantibodies against aquapori ..read more

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Simultaneous targeted and discovery-driven clinical proteotyping using hybrid-PRM/DIA

BMC | Clinical Proteomics

by Sandra Goetze, Audrey van Drogen, Jonas B. Albinus, Kyle L. Fort, Tejas Gandhi, Damiano Robbiani, Véronique Laforte, Lukas Reiter, Mitchell P. Levesque, Yue Xuan and Bernd Wollscheid

2w ago

Clinical samples are irreplaceable, and their transformation into searchable and reusable digital biobanks is critical for conducting statistically empowered retrospective and integrative research studies. Cur ..read more

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Correction: Proteomic signature associated with chronic kidney disease (CKD) progression identified by data-independent acquisition mass spectrometry

BMC | Clinical Proteomics

by Carlos R. Ramírez Medina, Ibrahim Ali, Ivona Baricevic-Jones, Aghogho Odudu, Moin A. Saleem, Anthony D. Whetton, Philip A. Kalra and Nophar Geifman

3w ago

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Quantitative proteomic analysis of HER2 protein expression in PDAC tumors

BMC | Clinical Proteomics

by Jamie Randall, Allison L. Hunt, Aratara Nutcharoen, Laura Johnston, Safae Chouraichi, Hongkun Wang, Arthur Winer, Raymond Wadlow, Jasmine Huynh, Justin Davis, Brian Corgiat, Nicholas W. Bateman, John F. Deeken, Emanuel F. Petricoin, Thomas P. Conrads and Timothy L. Cannon

1M ago

Metastatic pancreatic adenocarcinoma (PDAC) is the third leading cause of cancer-related death in the United States, with a 5-year survival rate of only 11%, necessitating identification of novel treatment par ..read more

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Human tear film protein sampling using soft contact lenses

BMC | Clinical Proteomics

by Robert K. Roden, Nathan Zuniga, Joshua C. Wright, David H. Parkinson, Fangfang Jiang, Leena M. Patil, Rebecca S. Burlett, Alyssa A. Nitz, Joshua J. Rogers, Jarett T. Pittman, Kenneth L. Virgin, P. Christine Ackroyd, Samuel H. Payne, John C. Price and Kenneth A. Christensen

1M ago

Human tear protein biomarkers are useful for detecting ocular and systemic diseases. Unfortunately, existing tear film sampling methods (Schirmer strip; SS and microcapillary tube; MCT) have significant drawba ..read more

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Proteomics of prostate cancer serum and plasma using low and high throughput approaches

BMC | Clinical Proteomics

by Ghaith M. Hamza, Rekha Raghunathan, Stephanie Ashenden, Bairu Zhang, Eric Miele and Andrew F. Jarnuczak

1M ago

Despite progress, MS-based proteomics in biofluids, especially blood, faces challenges such as dynamic range and throughput limitations in biomarker and disease studies. In this work, we used cutting-edge prot ..read more

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Neat plasma proteomics: getting the best out of the worst

BMC | Clinical Proteomics

by Ines Metatla, Kevin Roger, Cerina Chhuon, Sara Ceccacci, Manuel Chapelle, Pierre-Olivier Schmit, Vadim Demichev and Ida Chiara Guerrera

1M ago

Plasma proteomics holds immense potential for clinical research and biomarker discovery, serving as a non-invasive "liquid biopsy" for tissue sampling. Mass spectrometry (MS)-based proteomics, thanks to improv ..read more

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Correction to: Using phosphoproteomics data to understand cellular signaling: a comprehensive guide to bioinformatics resources

BMC | Clinical Proteomics

by Sara R. Savage and Bing Zhang

1M ago

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