Oncological care increasingly relies on molecular tumour characterization techniques to enhance patient outcomes. However, the clinical utility of some of these methods remains uncertain, potentially affecting their integration into healthcare systems. With all these new advancements, it can be a challenge to stay up to date on the clinical applications and future prospects of these precision oncology techniques. Join us for our latest webinar series, Molecular Analysis for Precision Oncology ONLINE, where we’ll hear insights from nine leading experts in the cancer genomics field, covering cut ..read more

‘World of Genomics: Estonia’ – Original article written by Shannon Gunn, 2021. Updated by Lyndsey Fletcher, April 2024. For the latest World of Genomics, we head over to Estonia – famous for its dense woodlands, charming historic sites in the old town of Tallinn and for having over 2,000 islands. Estonia has made great progress in the field of genetics, and also has an important indigenous heritage that has been vital in expanding its genomics reach. The population of Estonia Estonia is a country in Northern Europe that is bordered by Sweden, Latvia and Russia. It also has coastlines along the ..read more

On average, it takes 10.5 years for a Phase I drug to progress to regulatory approval and only ~8% of drugs get approved. The top contributing factors that spearhead drug candidate success are target identification and validation. Hence, the role of genomics in revolutionizing the way we discover, develop, and personalize drugs is becoming increasingly central. Join us for our latest webinar series: Genomics in Drug Discovery ONLINE as we unveil the latest genomics-driven advances that are broadening the drug discovery toolkit. This series will showcase how an enhanced accuracy in identifying ..read more

Next generation sequencing, both short reads and long reads, is undergoing a second wave of exciting developments. New short-read platforms have been released and the accuracy and quality from long-read methods is getting better and better, to the point where they are comparable to short reads. How are you to know which is the best method for your application? What about the best practices for sample prep? For NGS data analysis? Should you use single-cell sequencing? To help guide you through this journey, we are publishing The Sequencing Buyer’s Guide. This is the 6th edition of our ..read more

In this week’s World of Genomics, we explore the Philippines, an archipelago in Southeast Asia famous for its stunning natural beauty, rich culture and warm hospitality. While the country is renowned for its vibrant traditions and breathtaking landscapes, its presence in the field of genomic medicine is also gaining attention. In recent years, the Philippines has seen advancements in personalised health initiatives and genomics research, showing its commitment to genomic medicine. The Population of the Philippines The Philippines is a diverse nation comprising thousands of islands in the weste ..read more

Proteomics is the study of the entire set of proteins (known as the proteome) produced by a cell, tissue or organism. Proteins are large, complex polypeptides that play crucial roles in virtually all biological processes, including maintaining the structure and function of cells. Proteomics as a concept has been around for a while, but has recently found itself in the spotlight due to new and improved technical methods. In this feature, we explore the State Of the current proteomics research landscape and the past, present and future of the field. The past The central dogma of molecular biolog ..read more

It’s been a busy week with the Festival of Genomics and Biodata taking place in London, but there was plenty of research going on elsewhere! In this Week in Brief, we explore the latest news. Scientists have been working hard using genetic data to predict disease development… A new technique, dubbed ‘causal-Transcriptome-wide Association studies’, uses GWAS data and advanced statistical methods to more accurately predict which genes are involved in disease (Nature Genetics). A combination of retinal imaging and genetic data can be used to predict an individual’s risk of systemic diseases, acc ..read more

Original article written by Poppy-Jayne Morgan, July 2022. Updated by Aleisha Collins, January 2024. In this instalment of World of Genomics, we explore key aspects of South Africa’s diverse population, the intricacies of its healthcare system and its burgeoning capabilities in the field of genomics. Still feeling the effects of decades of inequality and under-resourcing, South Africa continues to face significant challenges. With high rates of tuberculosis and HIV, South Africa aims to reduce its disease burden through medical innovations and cutting-edge genomics advancements. As a leader in ..read more

In the age of large-scale omics data, we often find ourselves discussing the merits of genomics, proteomics and transcriptomics. But lesser discussed is metabolomics – the study of small molecules, metabolites, within cells. The overarching goal of metabolomics is to characterise these molecules and their interactions within their biological environment. Despite its potential, metabolomics is considered a relatively novel part of the multiomics toolbox. Metabolomics research is now on the rise and technology is becoming more advanced. That said, challenges still remain. In this feature, we ass ..read more

Drug discovery can be a long and gruelling process, but this effort is vital to advance human health. As is the case in many fields, the increasing sophistication of genomics and other omics, quantified at single-cell and spatial resolution, have, and will continue to, improve the process. However, genomic data has in fact played a role in this process for a long time now, and it persists as a staple tool in the drug discovery journey. In this feature, we take a look at the state of genomics in the drug discovery field, and dive into the past, present and future to give you a comprehensive ove ..read more