Current Advancements and Potential Applications of Nanocomposite Hydrogels in Dentistry: A Systematic Review
Nanomedicine Research Journal
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3M ago
Nanotechnology is applied in many scientific domains because it provides a variety of practical answers to scientific and medical problems. This systematic literature review using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) method to analyze nanocomposite hydrogels (NCHGs) in dentistry. Based on the results of a literature review study on 40 articles, NCHGs have the potential for antibacterial agents, tissue engineering, drug delivery systems, dental materials, etc. The present review aims to provide a depth analysis of NCHGs, impart on the recent advancemen ..read more
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The effect of ZrO2 NPs addition on denture adaptation and diametral compressive strength of 3D printed denture base resin
Nanomedicine Research Journal
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3M ago
Objective(s): The world of dentistry is constantly evolving, and with the advent of 3D printing technology, the possibilities are endless. However, little is known about the effects of adding ZrO2 NPs to the denture base resin of 3D additive manufacturing technique.Aim of this study is to evaluate the behavior of resin which is used to 3D printing of denture base with the addition of ZrO2 NPs on denture adaptation property and diametral compression strength.Methods: 60 samples were printed, 30 disks for diametral compressive test and 30 denture base for denture adaptation test. Three groups pe ..read more
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Electrodeposition of nano tin film on different substrates in a choline chloride–ethylene glycol deep eutectic solvent containing boric acid
Nanomedicine Research Journal
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3M ago
In recent years, Tin has been used in coating of medical and orthopedic instruments, probes, alignment devices, implants and surgical cutting tools. This study examines the electrodeposition of nano tin film on several substrates, including brass, copper, and mild steel, while using a ChCl: EG-based liquid which also contained boric acid. It was found that adding larger amounts of boric acid improved the conductivities of Sn electrolytes; when boric acid was introduced to them, the redox current peaks of Sn decreased with increasing concentrations of boric acid and displayed negative shifts in ..read more
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Exosomes derived from human dental stem cell enhance the viability of odontoblasts
Nanomedicine Research Journal
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3M ago
Objective(s): The purpose of this study was to assess the effects of exosomes derived from dental pulp mesenchymal stem cells (DPSCs) on the viability of odontoblast cells.Methods: Exosomes were extracted from human DPSC cells via ultracentrifugation. Scanning electron microscopy and western blot analysis for CD9 and CD81 demonstrated characteristics of exosomes. Developing odontoblasts were exposed to increasing concentrations of exosomes (10-400 ng/ml) over time periods of 24, 48, 72, and 96 hours. Cell viability was evaluated using MTT assays. In addition, real-time PCR was used to assess e ..read more
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Anti-cancerous effect and biological evaluation of green synthesized Selenium nanoparticles on MCF-7 breast cancer and HUVEC cell lines
Nanomedicine Research Journal
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3M ago
Green synthesis of nanoparticles is a safe and cost-effective process for creating nanoparticles using extracts from different parts of plants, such as flowers, leaves, stems, and roots. In this research, Melissa Officinalis L. (MO) aqueous extract was used for the synthesis of Selenium nanoparticles (Se NPs) for the first time. These extracts contain flavonoids, polyphenols, and alkaloids, which act as reducing agents in synthesizing nanoparticles. In this study, the extract serves both as a reducing agent and a capping agent during the fast and simple green synthesis of Selenium nanoparticle ..read more
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Green Synthesis of Gold Nanoparticles using Melissa Officinalis L. Aqueous Extract: Optimization, Antioxidant Activity and In Vitro Cell Viability
Nanomedicine Research Journal
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3M ago
Gold nanoparticles possess attractive properties that make them valuable in medicine. Recently, green synthesis of nanoparticles has been a target of research due to its simplicity, safety, eco-friendliness and cost-effectiveness. This study describes the green synthesis of gold nanoparticles via aqueous extract of Melissa officinalis L. (Mel). The various parameters affecting the synthesis of gold nanoparticles (pH, gold salt concentration, extract volume, temperature, and reaction time) were investigated and optimized. Ultraviolet–Visible spectrophotometry, Dynamic light scattering ..read more
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Norfloxacin Adsorption on the Surface of B12N12 and Al12N12 Nanoclusters: A Comparative DFT Study
Nanomedicine Research Journal
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3M ago
A recent study conducted using density functional theory computations has shed light on the potential use of B12N12 and Al12N12 nanoclusters as adsorbents and sensing materials for the removal and electrochemical detection of norfloxacin (NFX). The results of the study indicated that both B12N12 and Al12N12 nanoclusters are feasible options for the removal of NFX, with B12N12 being more suitable as an adsorbent and Al12N12 being a better option as a sensing material for electrochemical detection. The thermodynamic parameters of the study showed that NFX adsorption on B12N12 is a spontaneous, e ..read more
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Neuroprotective effects of cobalt ferrite nanoparticles coated with sumac on damaged sciatic nerve recovery
Nanomedicine Research Journal
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3M ago
Objective(s): Although damaged peripheral nerves have the ability to repair, axon regeneration proceeds slowly and often poor functional results are observed. Many methods are used to repair peripheral nerve lesions, but very few have demonstrated clinical success. Hence, the intention of the present study was to explore the regenerative outcomes of cobalt ferrite nanoparticles coated with sumac on rat sciatic nerve injury.Methods: Forty male Wistar rats were separated into four groups: the sham group (surgery without damage to the nerve), the negative control (nerve compression without nanopa ..read more
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Fabrication and modeling of nanocomposites with bioceramic nanoparticles for rapid wound healing: An experimental and molecular dynamics investigation
Nanomedicine Research Journal
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3M ago
In the present study, Fabrication and modeling of nanocomposites with bioceramic nanoparticles for rapid wound healing with (0wt. %, 5wt. %, 10wt. %, 15wt. % NPs) were investigated. After the fabrication of nanocomposites using the freeze-drying technique, X-ray diffraction (XRD) test is performed to show the crystallinity of hydroxyapatite and titanium oxide. Scanning electron microscopy (SEM) tests are performed to demonstrate the morphology of the structure, atomic force microscope (AFM) test is performed to show surface roughness and pores. Finally by placing nano scaffolds in a simulated ..read more
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Fabrication and modeling of nanocomposites with bioceramic nanoparticles for rapid wound healing: An experimental and molecular dynamics investigation
Nanomedicine Research Journal
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6M ago
In the present study, novel scaffolds are fabricated that consisting of Polycaprolactone (PCL) as a thermoplastic and biocompatible polymer and two bioceramic nanoparticles including Titanium oxide (TiO2) and Hydroxyapatite (HA) as reinforcements of the nanocomposites with (0wt. %, 5wt.%, 10wt.%, 15wt.%) of TiO2. After the fabrication of nanocomposites using the freeze-drying technique, X-ray diffraction (XRD) test is performed to show the crystallinity of hydroxyapatite and titanium oxide. Atomic force microscope (AFM) test is performed to show surface roughness and pores. Finally by placing ..read more
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