COVID-19 Pandemic Has Exacerbated CRC Surgery Disparities
Cancer Network | Colorectal Cancer
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2h ago
Patients who are African American appeared to have worse clinical stages of colon and rectal cancer during surgery in 2020 ..read more
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ME-344/Bevacizumab Combo Shows Early Efficacy in mCRC
Cancer Network | Colorectal Cancer
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2h ago
ME-344 and bevacizumab can now have an additional 20 patients enrolled on the phase 1b trial for relapsed metastatic colorectal cancer ..read more
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Blood-Based Test May Help Detect CRC in Average-Risk Population
Cancer Network | Colorectal Cancer
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1w ago
The PREEMPT trial analyzed samples from 27,010 average-risk adults to determine the specificity of detecting colorectal cancer ..read more
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Adagrasib Combo Yields Encouraging Responses in KRAS G12C–Mutated CRC
Cancer Network | Colorectal Cancer
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1w ago
Data from the phase 1/2 KRYSTAL-1 trial may support adagrasib plus cetuximab as a new standard in previously treated metastatic KRAS G12C–mutated CRC ..read more
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Personalized Vaccine Yields Early PFS Benefit in Metastatic MSS-CRC
Cancer Network | Colorectal Cancer
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3w ago
Long-term circulating tumor DNA responses appear to align with progression-free survival trends in a phase 2/3 trial of the GRANITE vaccine in those with microsatellite-stable colorectal cancer ..read more
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Microbiome Signature Differences May Impact Rectal Cancer Treatment Effect
Cancer Network | Colorectal Cancer
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3w ago
Gut microbiome signatures may lead the way for more accurate treatments and diagnoses for patients with colorectal cancer ..read more
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CRC-Associated Gene Alteration May Raise Likelihood of Other Solid Tumors
Cancer Network | Colorectal Cancer
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3w ago
If possible, targeting the BER pathway for drug sensitivities may increase therapeutic options for managing solid cancers, wrote Channing Paller, MD ..read more
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Novel Drug Shows Increased Efficacy in Small Metastatic CRC Population
Cancer Network | Colorectal Cancer
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1M ago
Results from part 3 of the phase 2a CORIST trial found that combining SCO-101 with chemotherapy improved the progression-free survival and clinical benefit rate in patients with metastatic colorectal cancer ..read more
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Cancer Vaccine Shows Efficacy and Safety Potential in PDAC and CRC
Cancer Network | Colorectal Cancer
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1M ago
Investigators of the AMPLIFY-201 trial hypothesized that ELI-002 2P may induce the expansion of functional tumor-directed KRAS-mutated specific T cells following tumor resection ..read more
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CtDNA-Based Negative Hyperselection May Guide Treatment Selection in mCRC
Cancer Network | Colorectal Cancer
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1M ago
Panitumumab plus modified FOLFOX6 appears to increase survival among patients with metastatic colorectal cancer and circulating tumor DNA that has no gene alterations in the PARADIGM trial ..read more
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