I Need a Study (or a very official source) proving that Double Chin / Submental Fullness / Submental Fat is Hereditary / Genetic submitted by /u/fac11111 [visit reddit] [comments ..read more

I'm a third year undergrad studying plant science with a minor in genetics. I've been in a cotton genomics research lab for the past three years and absolutely love it. So much that I decided I want to go into research and pursue a PhD. My GPA isn't where it needs to be (2.6), and after my rough semester I see it tanking more. If I drop my minor I can graduate on time, but if I keep it I'll be a year behind. My major doesn't require all the chem and biochem classes needed for the minor, but I'm scared I can't get into grad school without it. Does anyone have advice for my situation? I'm sinki ..read more

submitted by /u/Pretend_Paramedic_10 [visit reddit] [comments ..read more

Hello everyone, I have a question: how can I distinguish or determine whether a genetic variant (f.e. WES) seen on IGV is heterozygous, mosaic, or a PCR duplicate? submitted by /u/ExtremeGenetics700 [visit reddit] [comments ..read more

I have a question I'm hoping some of you bright minds can help with. In reviewing DNA sequencing data, if a person shows a deletion of shank3 at 22q.13.33 and it is also AD, is that definitive information for that person to have 22q13 deletion syndrom / phelan mcdermid? Are there other potentially protective genes that would make that deletion unremarkable or other genes that would 'neutralize' the effects of that deletion? I guess I'm asking is there anything else to look at DNA wise in order to be able to come to a positive determination of that individual having that deletion syndrome? The ..read more

Hi y'all, I'm new to the C. elegans model, and I was wondering what genetic tools can be used. When I worked with E. coli, we would use electroporation to insert a plasmid into the cells to express a gene. In rodents, sometimes rAAV is used. What would be the equivalent for C. elegans? Essentially, could I use rAAV to insert something like a gene construct that contained GFP with a specific promoter into C. elegans? (The construct I have in mind already exists and is used congenitally in a mutant strain, I was just wondering if it can be delivered via rAAV or something similar). submitted by ..read more

I am doing a project on ceramic dog effigies from Pre-Columbian West Mexican shaft tombs. One of these statues appears to depict a pair of conjoined dogs, can dogs actually be born and survive as conjoined twins? submitted by /u/nonbearingwall [visit reddit] [comments ..read more

submitted by /u/TheMuseumOfScience [visit reddit] [comments ..read more

Is it true that in episomal vectors for gene delivery, scientists can use the episomes from yeasts to deliver a large piece of gene that can be millions of base pairs long into the cell nucleus, and those episomes can transfect non-dividing cells such as neuron? Does it mean that unlike plasmids, the episomes don't need to rely on the breakdown of the nuclear membrane during cell proliferation to get into the nucleus? If so, do episomes enter the nucleus through the pores on the nuclear membrane? If they have millions of bases pairs, how could they possibly fit into those pores that are extre ..read more

Disclaimer: I am black It seems to me that the consensus is that intelligence is heritable. I understand that we are not 100% sure as to how intelligence works and how to measure it (IQ is probably not a good measure). But, even with these limitations, we know it’s hereditary. If that’s the case, how is there no correlation between intelligence and belonging to a certain human group (ethnic, racial, linguistic, national origin, or whatever)? It seems to me that it has to be true by definition. Why would it be wrong to say that people from group X are, on average, less intelligent than people ..read more