Can a Smell Test Sniff Out Alzheimer’s Disease?
DementiaToday
by dementiatoday
3y ago
(Journal of Alzheimer’s Disease) The sense of smell is one of the first things to change as Alzheimer’s disease takes root, even before other symptoms appear. That’s raised the idea that a scratch-and-sniff test that rates an individual’s ability to identify odors could potentially detect the disease early – allowing patients to begin treatment before symptoms become harder to treat. Columbia neurologist William Kreisl, MD, has been studying a smell identification test and explains what it can – and can’t – say about Alzheimer’s. What’s the connection between smell and Alzheimer’s disease? The ..read more
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Disrupted Sleep-Wake Cycle Might be Measure for Preclinical Alzheimer’s
DementiaToday
by dementiatoday
3y ago
(NIH) People with dementia due to Alzheimer’s disease are known to have disrupted sleep. New NIH-funded research, published online Jan. 29, 2018, in JAMA Neurology, links a disrupted sleep-wake cycle to an earlier, preclinical disease phase, in which people have evidence of the disease but no symptoms. The study, by researchers at the Knight Alzheimer’s Disease Research Center at Washington University in St. Louis, Missouri, suggests that a fragmented sleep-wake cycle might be explored as a biomarker for preclinical Alzheimer’s. For the study, 189 people (average age, 66 years) wore watch-like ..read more
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Scientists Push Plan To Change How Researchers Define Alzheimer’s
DementiaToday
by dementiatoday
3y ago
(NPR, Jon Hamilton) An international coalition of brain researchers is suggesting a new way of looking at Alzheimer’s. Instead of defining the disease through symptoms like memory problems or fuzzy thinking, the scientists want to focus on biological changes in the brain associated with Alzheimer’s. These include the plaques and tangles that build up in the brains of people with the disease. But they say the new approach is intended only for research studies and isn’t yet ready for use by most doctors who treat Alzheimer’s patients. If the new approach is widely adopted, it would help res ..read more
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What’s New in the Alzheimer’s Treatment Pipeline?
DementiaToday
by dementiatoday
3y ago
(BrightFocusFoundation, James M. Ellison, MD, MPH) Learn about potential new treatments for Alzheimer’s disease that may help manage current symptoms, but also improve outcome over the longer term by changing the course of the disease. Despite the great need for more effective Alzheimer’s disease (AD) treatments, no really new or different medication has been approved by the FDA for this purpose in over a decade. Recently, Dr. Jeffrey Cummings and his colleagues took a bird’s eye view of the current drug development pipeline.1 They identified 105 distinct agents being tested in 2017, of which ..read more
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