Strategizing New Product Development in the Personal Care 4.0 Era
Pharmaceutical Microbiology
by Dr Tim Sandle
3d ago
As we navigate a period centered on self-care and sustainable practices, businesses must confront the challenges of keeping pace with the evolving industry trends, staying informed about the regulatory changes across different geographies, and thoroughly considering swiftly changing technologies & consumer preferences, especially while developing and launching cosmetic products in the market. For this, choosing the right approach/ strategy is imperative.   By Nitin Jindal Ingenious e-Brain, with its bespoke consulting services, has come up with a revolutionary model, “Personal ..read more
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The Intersection of AI and Radiology: A Look into the Future
Pharmaceutical Microbiology
by Dr Tim Sandle
1w ago
  Radiology has long been an essential component of modern healthcare, providing vital insights into the human body through imaging techniques such as X-rays, MRIs, and CT scans. With advancements in technology, particularly in artificial intelligence (AI), the field of radiology is experiencing a profound transformation. In this blog post, we will explore how AI is revolutionizing radiology software and shaping the future of diagnostic imaging. By Emma Sturgis Enhanced Image Analysis One of the most significant contributions of AI to radiology software is its ability to improve image ..read more
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Introducing the Burkholderia cepacia complex
Pharmaceutical Microbiology
by Dr Tim Sandle
2w ago
Image: CDC/Janice CarrContent Providers: Public Health Image Library (PHIL). Public Domain, https://commons.wikimedia.org/w/index.php?curid=2208169 Members of the Burkholderia cepacia complex (BCC), of which there are 18 different species, which are grouped into nine genomovars. These are aerobic organisms, widely distributed, and found in soil and water[i]. Importantly they can additionally survive for long periods in low-nutrient moist environments[ii], which make these organisms probable survivors within pharmaceutical grade water systems. By Tim Sandle B. cepacia is a human opportunist ..read more
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Medicare Advantage Explained: A Comprehensive Guide to Your Options
Pharmaceutical Microbiology
by Dr Tim Sandle
3w ago
Medicare Advantage, also known as Part C, is a private insurance alternative to the traditional Medicare program. If you're among the millions of Americans who are either enrolled in Medicare or approaching eligibility, understanding your Medicare Advantage options is crucial. With nuances and plans aplenty, it's a substantial decision that requires comprehensive comprehension. Here's a tailored walkthrough on what Medicare Advantage entails and how to assess your choices wisely. By Rianne Hunter Medicare Advantage Defined Medicare Advantage plans, sold by private companies approved by Medi ..read more
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5 Tips for Managing Chronic Disease
Pharmaceutical Microbiology
by Dr Tim Sandle
3w ago
Living with a chronic disease can be challenging, but there are many practical tips and tools available to help manage symptoms and improve quality of life. From making dietary changes to utilizing technology like configurable remote patient monitoring, there are numerous strategies that can make a difference in managing chronic conditions. In this article, we will explore some practical tips for managing chronic disease and how they can benefit those living with long-term health issues. By Riley Smith Diet Diet plays a crucial role in managing chronic diseases such as diabetes, heart diseas ..read more
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A Public Health Expert’s Ultimate Guide to Handwashing
Pharmaceutical Microbiology
by Dr Tim Sandle
3w ago
Researchers estimate that one million deaths could be prevented annually if every person practiced proper hand hygiene. Handwashing is among the most effective tools one can use to avoid catching or spreading disease, yet research shows that handwashing is a skill imperfected by many. For example, a study done by the U.S Department of Agriculture (USDA) regarding hand washing before meals, revealed consumers fell short of adequate washing 97% of the time. Similarly, a study observing hand washing after bathroom use at various public attractions in major cities found as many as 15% of people ..read more
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Best practices for pharmaceutical microbial data investigations
Pharmaceutical Microbiology
by Dr Tim Sandle
1M ago
 Investigating. Image designed by Tim Sandle Assessing microbiological data and undertaking investigations into the origins of contamination, establishing root causes, and setting appropriate preventative actions constitutes a core part of the contamination control strategy. Despite the importance of this process, regulatory findings frequently cite poor quality microbial investigations.   This article looks at the main steps involved for conducting investigations and provides some best practice advice for the company microbiologist. The goals here are to help to structure investig ..read more
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Disinfectant efficacy: Getting the temperature right
Pharmaceutical Microbiology
by Dr Tim Sandle
1M ago
 Apart from a few exceptions, disinfection processes are considerably slower at low temperatures than at higher temperatures. This carries consequences for the use of disinfectants, especially in cold rooms where ‘cold-loving’ microbes present a contamination risk. To address this, either concentrations or contact times need to be increased, or an alternative disinfectant agent used. In this article, we take a look at the science. Read the article for fre online: Sandle, T. Disinfectant efficacy: Getting the temperature right, RRSL Life Sciences Series, 20th March 2023 at: https://www ..read more
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Identifying origin of fungi in cleanrooms
Pharmaceutical Microbiology
by Dr Tim Sandle
1M ago
 Image: Tim Sandle Pharmaceutical product recalls due to fungal contamination have been increasing. These, together with environmental monitoring trend data, highlight several fungal contamination issues associated with pharmaceutical cleanrooms, cold rooms and other controlled areas. Species of filamentous mould include: Cladosporium, Penicillium, Aspergillus, Alternaria, Fusarium, and Paecilomyces). Read the article free online: Eckford, C. and Sandle, T.(2023) Identifying origin of fungi in cleanrooms, European Pharmaceutical Review, 22 March 2023: https://www.europeanpharmaceutica ..read more
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Covalent, Non-covalent, and Covalent Reversible Drug Design in Medicinal Chemistry
Pharmaceutical Microbiology
by Dr Tim Sandle
1M ago
 Image: By Boghog2 - Own work, Public Domain, https://commons.wikimedia.org/w/index.php?curid=7078192 Chemical drugs can be classified into three categories based on their binding modes: covalent drugs, non-covalent drugs, and covalent reversible drugs. Covalent drugs have strong binding ability and high efficacy, but they also come with strong toxic side effects. Non-covalent drugs have generally weaker binding ability, shorter duration of action, and relatively milder toxic side effects. Covalent reversible drugs, positioned between the other two categories, are considered relatively ..read more
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